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9 3 B1.1 Biochemistry and molecular biology + %Ҥǡ .Էʵᾷ鹰ҹ ; 5 Ǵ 1. B1 ѡ÷ (General principle) @ : B1.1.1 Structure, and function of proteins O I B1.1.1.1 principles of protein structure and folding J D B1.1.1.2 enzymes: kinetics, reaction mechanisms e _ B1.1.1.3 structural and regulatory proteins: ligand binding, self-assembly 9 3 B1.1.1.4 regulatory properties V P B1.1.2 Gene expression: DNA structure, replication, and exchange t
n B1.1.2.1 DNA structure: single- and double-stranded DNA, stabilizing forces, supercoiling f ` B1.1.2.2 gene structure and organization: chromosomes, centromere, telomere o i B1.1.2.3 DNA replication, degradation, repair, mutation, activation and inactivation R
L B1.1.2.4 recombination, insertion sequences, transposon ] W B1.1.2.5 mechanisms of genetic exchange, including transformation N H B1.1.3 Gene expression: transcription, including defects W Q B1.1.3.1 transcription of DNA into RNA, RNA, RNA degradation E ? B1.1.3.2 post-transcriptional modification v p B1.1.3.3 regulation: cis-regulatory elements, transcription factors, enhancers, promoters, L F B1.1.4 Gene expression: translation, including defects 4 . B1.1.4.1 the genetic code B < B1.1.4.2 structure and function of tRNA G A B1.1.4.3 structure and function of ribosomes 5 / B1.1.4.4 protein synthesis = 7 B1.1.4.5 regulation of translation D > B1.1.4.6 post-translational modifications ? 9 B1.1.5 Principles of molecular technology x r B1.1.5.1 analysis of DNA: sequencing, restriction analysis, PCR, amplification, hybridization ? 9 B1.1.5.2 plasmids and bacteriophages 0 * B1.1.5.3 gene cloning N H B1.1.5.4 recombinant DNA technology and application Y S B1.1.6 Energy metabolism, including metabolic sequences, regulation u o B1.1.6.1 cellular bioenergetic: thermodynamics, free energy, chemical equilibria and group n ! h B1.1.6.2 tricarboxylic acid cycle, electron transport and oxidative phosphorylation t "